簡要描述：StemRD GDC-0449, SMO antagonist 拮抗劑
GDC-0449 （Vismodegib）: A potent antagonist of SMO （smoothened）. This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molec

產品英文名稱: GDC-0449, SMO Antagonist
產品中文名稱: GDC-0449, SMO 拮抗劑

GDC-0449, SMO Antagonist 產品英文簡述:
GDC-0449 (Vismodegib): A potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
 
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.

華雅再生醫學工程技術有限公司是一家為干細胞研究員提供干細胞無血清培養基，支原體檢測試劑盒，心肌細胞株，人間充質干細胞株，凍存管凍存盒，臍帶間充質干細胞凍存袋，細胞實驗耗材等進口品牌高質量產品。專注干細胞研究，關注干細胞治療產品，購買干細胞產品請到華雅再生醫學工程公司。